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  1. alieniags
    alieniags says:

    81 As introduced previously, this evidence confirms that reduced IGF I signaling can have both a positive and a negative impact on cardiovascular function during stress and aging, a dichotomy that may be explained by the well established role of IGF I and of IGF I signaling proteins in acting acutely to block apoptosis but in promoting cellular sensitivity to stress in response to chronic exposure see Growth Signaling and Stress Resistance in Mammals stromectol 12 mg buy


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